Recombinant Human PPIase B/PPIB(C-6His)
|Alternative Name :||CYP-S1; CYPB; HEL-S-39; OI9; SCYLP|
|Amount :||50 µg|
Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.
|Content :||Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4.|
|Amino acid sequence :||Recombinant Human Peptidyl-prolyl cis-trans isomerase B is produced by our Mammalian expression system and the target gene encoding Asp34-Ala212 is expressed with a 6His tag at the C-terminus.|