Recombinant Mouse Interleukin-2/IL2
|Amount :||50 µg|
|Content :||Lyophilized from a 0.2 µm filtered solution of 20mM Sodium Citrate, 5% Trehalose, pH4.5.|
|AA sequence :||Recombinant Mouse Interleukin-2 is produced by our E.coli expression system and the target gene encoding Ala21-Gln169 is expressed.|
|Alternative Name :||aldesleukin, interleukin 2, interleukin-2, IL-2, IL2, T-cell growth facter, T cell growth factor, TCGF , REF: C1025|
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL-2 shares 56% and 73% aa sequence identity with human and rat IL-2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma delta T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL-2 may be a key cytokine in the natural suppression of autoimmunity.