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  7. Anti-4-1BB Ligand antibody(DM68), Rabbit mAb

Anti-4-1BB Ligand antibody(DM68), Rabbit mAb

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Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human 4-1BB Ligand protein, mFc-His tagged protein can bind Rabbit anti-4-1BB Ligand monoclonal antibody (clone: DM68) in a linear range of 1-100 ng/ml.

Anti-4-1BB Ligand antibody(DM68), Rabbit mAb
Anti-4-1BB Ligand antibody(DM68), Rabbit mAb
Anti-4-1BB Ligand antibody(DM68), Rabbit mAb

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Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human 4-1BB Ligand protein, mFc-His tagged protein  can bind Rabbit anti-4-1BB Ligand monoclonal antibody (clone: DM68) in a linear range of 1-100 ng/ml.
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human 4-1BB Ligand (B) were surface stained with Rabbit anti-4-1BB Ligand monoclonal antibody 1µg/ml (clone: DM68) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 3. FACS data of serially titrated Rabbit anti-4-1BB Ligand monoclonal antibody (clone: DM68) on Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Product code: 12-9054

Clone name : DM68
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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100 µg
$599.00 

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  • Product Info
  • Antigen Details
  • Description
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Amount : 100 µg
Isotype : Rabbit IgG
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : 4-1BB Ligand,TNFSF9,CD137L
Immunogen Information : Recombinant human 4-1BB Ligand (Pro52-Glu254) produced by using human HEK293 cells

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

Recommended Dilutions ELISA 1/5000-10000;FACS  1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-4-1BB Ligand antibody(DM68), Rabbit mAb

Product code: 12-9054
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