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    7. Anti-Aurora B (Proliferation Marker) Monoclonal Antibody(Clone: AURKB/3121R)

    Anti-Aurora B (Proliferation Marker) Monoclonal Antibody(Clone: AURKB/3121R)

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    Fig. 1: Formalin-fixed, paraffin-embedded human Colon stained with Aurora B Rabbit Recombinant Monoclonal Antibody (AURKB/3121R).

    Anti-Aurora B (Proliferation Marker) Monoclonal Antibody(Clone: AURKB/3121R)
    Anti-Aurora B (Proliferation Marker) Monoclonal Antibody(Clone: AURKB/3121R)

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    Fig. 1: Formalin-fixed, paraffin-embedded human Colon stained with Aurora B Rabbit Recombinant Monoclonal Antibody (AURKB/3121R).
    Fig. 2: SDS-PAGE Analysis Purified Aurora B Rabbit Recombinant Monoclonal (AURKB/3121R). Confirmation of Purity and Integrity of Antibody.

    Product code: 36-3502

    Clone name : AURKB/3121R
    Clonality : Monoclonal
    Application : IHC
    Reactivity : Human

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    •   20 µg

    •  100 µg

    • $199.00 

    • $459.00 

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    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
    • Application Note
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    Amount : 100 µg
    Isotype : Rabbit IgG
    Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
    Gene : AURKB
    Gene ID : 9212
    Uniprot ID : Q96GD4
    Alternative Name : AIK2; AIM-1; ARK-2; AurB; AURKB; Aurora-1; Aurora and Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora-B; Aurora-related kinase 2; Aurora/IPL1-related kinase 2; IPL1; Protein phosphatase 1 regulatory subunit 48 (PPP1R48); Serine/threonine-protein kinase 12; Serine/threonine-protein kinase aurora-B; STK1; STK12; STK5
    Immunogen Information : Recombinant fragment (around aa 89-251) of human Aurora B protein (exact sequence is proprietary)
    Recognizes a protein of 39kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.

    Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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    Anti-Aurora B (Proliferation Marker) Monoclonal Antibody(Clone: AURKB/3121R)

    Product code: 36-3502
    *specify in mg or ml

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