Anti-Bim Monoclonal Antibody (Clone:Ham151-149)
Bim (Bcl2-interacting mediator) is a pro-apoptotic protein of BH3 domain-only subgroup of the Bcl2 family. It has important roles in initiation of apoptosis in response to many death stimuli. Bim is an important regulator of B and T cell negative selection and is also an essential regulator of T cell apoptosis during termination of an immune response. Bim is constitutively expressed in many cell types but it is maintained in an inactive form through binding to the microtubule-associated dynein motor complex.
|Purification :||Purified by protein-A affinity chromatography|
|Storage condition :||Store at 2-8°C. Do not freeze.|
Flow Cytometry Recommended dilution:10 µg / ml
Application note:Cells permeabilized with 0.03% saponin
Immunoprecipitation Recommended dilution: 1-2 µg /100-500 µg of protein in 1 ml lysate Western Blotting Recommended dilution: 1-2 µg / ml Application note:reducing conditions
Immunocytochemistry Application note:Permeabilized cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Tissue Specificity:||Expressed constitutively in roots.|
|BioGrid:||15986. 8 interactions.|