Anti-Bim Monoclonal Antibody (Clone:Ham151-149)(Discontinued)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Hamster IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Bim (Bcl2-interacting mediator) is a pro-apoptotic protein of BH3 domain-only subgroup of the Bcl2 family. It has important roles in initiation of apoptosis in response to many death stimuli. Bim is an important regulator of B and T cell negative selection and is also an essential regulator of T cell apoptosis during termination of an immune response. Bim is constitutively expressed in many cell types but it is maintained in an inactive form through binding to the microtubule-associated dynein motor complex.
Flow Cytometry Recommended dilution:10 µg / ml
Application note:Cells permeabilized with 0.03% saponin
Immunoprecipitation Recommended dilution: 1-2 µg /100-500 µg of protein in 1 ml lysate Western Blotting Recommended dilution: 1-2 µg / ml Application note:reducing conditions
Immunocytochemistry Application note:Permeabilized cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Tissue Specificity: | Expressed constitutively in roots. |
| BioGrid: | 15986. 8 interactions. |
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