Anti-Mouse CD106 Antibody (Clone : 429 (MVCAM.A))
Figure 1 : Flow cytometry surface staining pattern of murine bone marrow cell suspension stained using anti-mouse CD160 (429) purified antibody (concentration in sample 0,19 µg/ml) DAR APC.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rat IgG2a kappa |
| Purification : | Purified by protein-A affinity chromatography |
| Content : | 1 mg/ml Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Gene : | Vcam1 |
| Gene ID : | 22329 |
| Alternative Name : | Vcam-1,vascular cell adhesion molecule 1 |
| Immunogen Information : | Murine preadipose cell line PA6 |
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
Specificity : The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
Specificity : The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
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