Anti-C1QA / Complement C1q A-Chain Monoclonal Antibody(Clone: C1QA/2956)

Name: Anti-C1QA / Complement C1q A-Chain Monoclonal Antibody(Clone: C1QA/2956)
Brand: Abeomics
SKU: 36-3277
Price: 429.0000 USD
Availability: InStock
Rating: 5 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with C1QA Mouse Monoclonal Antibody (C1QA/2956).

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Fig. 1: Formalin-fixed, paraffin-embedded human Kidney stained with C1QA Mouse Monoclonal Antibody (C1QA/2956).

Fig. 2: Formalin-fixed, paraffin-embedded human Liver stained with C1QA Mouse Monoclonal Antibody (C1QA/2956).

Fig. 3: SDS-PAGE Analysis Purified C1QA Mouse Monoclonal Antibody (C1QA/2956). Confirmation of Purity and Integrity of Antibody.

Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using C1QA Mouse Monoclonal Antibody (C1QA/2956). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3277

Clone name :	C1QA/2956
Application :	IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS


Gene :	C1QA
Gene ID :	712
Uniprot ID :	P02745
Alternative Name :	Complement C1q subcomponent subunit A; Complement component 1 q subcomponent alpha polypeptide
Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Immunogen Information :	Recombinant fragment (around aa 104-237) of human C1QA protein (exact sequence is proprietary)

C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A throµgh C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drµgs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.

Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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