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  7. Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Polyclonal Antibody

Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Polyclonal Antibody

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Fig. 1: Formalin-fixed, paraffin-embedded human Hodgkin's Lymphoma stained with CD30 Rabbit Polyclonal Antibody.

Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Polyclonal Antibody

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Product code: 36-3583

Clonality : Polyclonal
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
  • Description
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Amount : 100 µg
Isotype : Rabbit IgG
Content : 200 µg/ml of Ab Purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : TNFRSF8
Gene ID : 943
Uniprot ID : P28908
Alternative Name : CD30L receptor, Cytokine receptor CD30, Ki-1 antigen, Lymphocyte activation antigen CD30, Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
Immunogen Information : Recombinant human TNFRSF8 protein fragment
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Immunohistochemistry (Formalin-fixed) (0.5-1µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Polyclonal Antibody

Product code: 36-3583
*specify in mg or ml

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