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  7. Anti-HLA-A+B+C+E Monoclonal Antibody (Clone:TP25.99SF)

Anti-HLA-A+B+C+E Monoclonal Antibody (Clone:TP25.99SF)

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Anti-HLA-A+B+C+E Monoclonal Antibody (Clone:TP25.99SF)

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Product code: 30-1580

Clone name : TP25.99SF
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$374.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Immunogen Information : IFN-gamma-treated human melanoma cells Colo 38

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Classical human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules, the non-classical by e.g. HLA-E, HLA-G.

Subcellular location: Membrane
Post transnational modification: Polyubiquitinated in a post ER compartment through interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system.
BioGrid: 109350. 90 interactions.
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Anti-HLA-A+B+C+E Monoclonal Antibody (Clone:TP25.99SF)

Product code: 30-1580
*specify in mg or ml

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