Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Immune-Check Point
        • Kits and Reagents
          • Luciferase reporter assay kits
          • Inhibitor Screening Kit
          • ELISA Kits
          • Molecular Biology Kits
          • Apoptosis Detection kits
          • Flowcytometry staining kits
          • Cell dissociation solutions
          • Western Blot membranes (Quick blots/ Q Blots)
        • Tissue Microarray
        • recmAb™
          • Recombinant Biosimilar Antibodies
          • Recombinant Rabbit Antibodies
          • Recombinant Mouse Antibodies
    • Pathways
        • All-Pathways

          View all pathways

        • interactive-pathways

          View all interactive pathways

    • Custom Service
      • Drug Discovery Screening Services
      • Stable Cell Line Development
      • Protein Production
      • Custom Antibody Development
    • Quick order
      • + Add More..

    • Support
    • Contact us
    • Distributors
    1. Catalog
    2. /
    3. Antibodies
    4. /
    5. Immunology
    6. /
    7. Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)

    Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)

    Share:

    Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)

    Roll over image to zoom in

       

    Product code: 30-1171

    Clone name : MEM-05
    Clonality : Monoclonal
    Application : ICC, IHC, FACS, WB
    Reactivity : Human

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS
    Write a review for this product on BioCompare
    Get $20 gift card from Amazon
    Size
    Price
    0.1 mg
    $339.00  $271.20 

    Add to Wish List

    Bulk Order

    Shipping Info:

    For estimated delivery dates, please contact us at support@abeomics.com

    Download TDS MSDS

    • Product Info
    • Antigen Details
    • Description
    • Application Note
    • More
    • Review   (0)
    Format : Purified
    Amount : 0.1 mg
    Isotype : Mouse IgG1
    Purification : Purified by protein-A affinity chromatography
    Storage condition : Store at 2-8°C. Do not freeze.
    Gene : PECAM1
    Gene ID : 5175
    Uniprot ID : P16284
    Alternative Name : PECAM1
    Immunogen Information : Leukocytes of patient suffering from LGL-type leukaemia

    CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

    Flow Cytometry Recommended dilution:1-10 µg/ml
    Western Blotting Application note: Non-reducing conditions

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

    Subcellular location: Cell junction
    Post transnational modification: Palmitoylation by ZDHHC21 is necessary for cell surface expression in endothelial cells and enrichment in membrane rafts.
    Tissue Specificity: Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells (PubMed:18388311, PubMed:21464369). Expressed in human umbilical vein endothelial cells (HUVECs) (at protein level) (PubMed:19342684, PubMed:17580308). Expressed on neutrophils (at protein level) (PubMed:17580308). Isoform Long predominates in all tissues examined (PubMed:12433657). Isoform Delta12 is detected only in trachea (PubMed:12433657). Isoform Delta14-15 is only detected in lung (PubMed:12433657). Isoform Delta14 is detected in all tissues examined with the strongest expression in heart (PubMed:12433657). Isoform Delta15 is expressed in brain, testis, ovary, cell surface of platelets, human umbilical vein endothelial cells (HUVECs), Jurkat T-cell leukemia, human erythroleukemia (HEL) and U-937 histiocytic lymphoma cell lines (at protein level) (PubMed:12433657, PubMed:18388311).
    BioGrid: 111201. 22 interactions.
    There are currently no product reviews
    Write a review on this product!

    Customers who purchased this product also purchased

    IL-10 (human):Fc (human) (Recombinant) (non-lytic)

    IL-10 (human):Fc (human) (Reco...

    details-IL-10 (human):Fc (human) (Recombinant) (non-lytic)
    Anti-beta-Actin Monoclonal Antibody (Clone: AC-15)

    Anti-beta-Actin Monoclonal Ant...

    details-Anti-beta-Actin Monoclonal Antibody (Clone: AC-15)
    Anti-Phosphotyrosine Monoclonal Antibody (Clone:P-Tyr-01)

    Anti-Phosphotyrosine Monoclona...

    details-Anti-Phosphotyrosine Monoclonal Antibody (Clone:P-Tyr-01)
    Anti-DLL4 PE (Clone : MHD4-46)

    Anti-DLL4 PE (Clone : MHD4-46)

    details-Anti-DLL4 PE (Clone : MHD4-46)
    Anti-ZAP-70 Polyclonal Antibody

    Anti-ZAP-70 Polyclonal Antibod...

    details-Anti-ZAP-70 Polyclonal Antibody
    Recombinant Human Secretoglobin Family 3A Member 2

    Recombinant Human Secretoglobi...

    details-Recombinant Human Secretoglobin Family 3A Member 2
    Monoclonal Antibody to mouse M-CSF

    Monoclonal Antibody to mouse M...

    details-Monoclonal Antibody to mouse M-CSF
    Alkaline phosphatase conjugated Goat anti Rabbit IgG (H+L)

    Alkaline phosphatase conjugate...

    details-Alkaline phosphatase conjugated Goat anti Rabbit IgG (H+L)
    Anti-HSP90 alpha/beta Monoclonal Antibody (Clone : Hyb-K41220A) APC(Discontinued)

    Anti-HSP90 alpha/beta Monoclon...

    details-Anti-HSP90 alpha/beta Monoclonal Antibody (Clone : Hyb-K41220A) APC(Discontinued)
    Biotin Conjugated, Anti-alpha-tubulin Monoclonal Antibody (Clone:TU-01)

    Biotin Conjugated, Anti-alpha-...

    details-Biotin Conjugated, Anti-alpha-tubulin Monoclonal Antibody (Clone:TU-01)
    Anti-IDH1 R132H Monoclonal Antibody (Clone:IHC132)

    Anti-IDH1 R132H Monoclonal Ant...

    details-Anti-IDH1 R132H Monoclonal Antibody (Clone:IHC132)
    Anti-CD95 / Fas Monoclonal Antibody (Clone:UT-1)-Azide free(Discontinued)

    Anti-CD95 / Fas Monoclonal Ant...

    details-Anti-CD95 / Fas Monoclonal Antibody (Clone:UT-1)-Azide free(Discontinued)
    Anti-Human CD34 PE-DyLight® 594 (Clone : 4H11[APG])

    Anti-Human CD34 PE-DyLight® 5...

    details-Anti-Human CD34 PE-DyLight® 594 (Clone : 4H11[APG])
    Anti-Thyrotropin (hTSH) Monoclonal Antibody (Clone:TSH-116)

    Anti-Thyrotropin (hTSH) Monocl...

    details-Anti-Thyrotropin (hTSH) Monoclonal Antibody (Clone:TSH-116)

    Most viewed Products

    Recombinant Human Thioredoxin-Like 4A

    Recombinant Human Thioredoxin-Like ...

    details-Recombinant Human Thioredoxin-Like 4A
    Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

    Monoclonal Antibody to Human IL-1be...

    details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
    NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

    NF-kB Leeporter™ Luciferase Repor...

    details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
    Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

    Monoclonal antibody to Human PD-L1 ...

    details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
    Polyclonal Antibody to Beta actin

    Polyclonal Antibody to Beta actin

    details-Polyclonal Antibody to Beta actin
    Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

    Monoclonal Antibody to Caspase-3 (P...

    details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
    Monoclonal Antibody to GAPDH (Clone: ABM22C5)

    Monoclonal Antibody to GAPDH (Clone...

    details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
    Monoclonal antibody to B7-H4 (Clone: ABM53A6)

    Monoclonal antibody to B7-H4 (Clone...

    details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
    Polyclonal Antibody to Beta Tubulin

    Polyclonal Antibody to Beta Tubulin

    details-Polyclonal Antibody to Beta Tubulin
    Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Peroxidase conjugated Goat anti Mou...

    details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

    Related Products

    Mouse Anti-Chicken CD45

    Mouse Anti-Chicken CD45

    Rat Anti-Mouse CD4-CY5

    Rat Anti-Mouse CD4-CY5

    Monoclonal Antibody to human TNF-alpha

    Monoclonal Antibody to human TNF-alpha

    close

    Please Login to write a Review !!


    close

    Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)

    Product code: 30-1171
    *specify in mg or ml

    Abeomics Logo

    Antibodies & Engineered Cell Lines™

    Tel : 858-263-4982

    Fax : 858-247-7052

    Email : support@abeomics.com

    Connect with Us

    • Facebook
    • Twitter
    • Linkedin
    • YouTube

    Products

    • Antibodies
    • Cell Lines
    • Ligands and Inhibitors
    • Recombinant Proteins
    • Immune-Check Point
    • Kits and Reagents
    • Tissue Microarray
    • recmAb™

    Services

    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development

    Quick order

    + Add More..

    Newsletter

    Posters and Flyers

    © 2022 Abeomics. All rights reserved.
    • Blog
    • Sitemap
    • Terms
    • Privacy Policy
    • Legal
    • Email unsubscribe

    Item added to cart successfully

    No cart item available
    Continue shopping View Cart