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  7. Anti-CD370 Antibody (Clone : 8F9)

Anti-CD370 Antibody (Clone : 8F9)

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Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD370 (8F9) purified antibody (concentration in sample 1,67 µg/ml) GAM FITC.

Anti-CD370 Antibody (Clone : 8F9)
Anti-CD370 Antibody (Clone : 8F9)
Anti-CD370 Antibody (Clone : 8F9)

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Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD370 (8F9) purified antibody (concentration in sample 1,67 µg/ml) GAM FITC.
Figure 2 : Flow cytometry multicolor surface staining of human myeloid cells stained using anti-human CD370 (8F9) purified antibody (concentration in sample 1,67 µg/ml, GAM FITC) and anti-human CD16 (3G8) APC antibody (10 µl reagent / 100 µl of peripheral whole blood).
Figure 3 :Separation of human CD370 positive CD16 positive dendritic cells (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD370 (8F9) purified antibody (concentration in sample 1,67 µg/ml) GAM FITC.

Product code: 30-2569

Clone name : 8F9
Clonality : Monoclonal
Application : FACS , ICC
Reactivity : Human

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0.1 mg
$399.00 

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  • Product Info
  • Antigen Details
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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG2a
Purification : Purified by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CLEC9A
Gene ID : 283420
Alternative Name : CLEC9A, DNGR1, DNGR-1, UNQ9341,C-type lectin domain containing 9A
Immunogen Information : RBL-2H3 cells expressing human CLEC9A fused to an HA epitope
CD370 / CLEC9A, also known as DNGR1, is a type II transmembrane glycoprotein with extracellular C-type lectin domain and intracellular ITAM-containing domain. Its expression is restricted to BDCA3+ conventional dendritic cells and to a subset of CD14+ CD16- monocytes. CD370 serves as a receptor for ubiquitous preformed acid-labile protein associated ligands that are exposed when the cell membrane is damaged, such as on necrotic cells. Its triggering by these ligands mediates recruitment and activation of the tyrosine kinase Syk and leads to their cross-presentation to the immune system.
Specificity : The mouse monoclonal antibody 8F9 recognizes an extracellular epitope of CD370 / CLEC9A (DNGR1), a type II transmembrane protein functioning as an endocytic receptor on BDCA31+ dendritic cells and on a subset of CD14+ CD16- monocytes.
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Anti-CD370 Antibody (Clone : 8F9)

Product code: 30-2569
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