Anti-PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody(Clone: PMEPA1/2698)
Fig. 1: Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2698).
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| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | PMEPA1 |
| Gene ID : | 56937 |
| Uniprot ID : | Q96W9 |
| Alternative Name : | PMEPA; PMEPA1; Prostate transmembrane protein, androgen induced 1; Solid tumor-associated 1 protein; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Transmembrane, prostate androgen induced RNA |
| Immunogen Information : | Recombinant full-length human PMEPA1 protein |
PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, sµggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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