Anti-CD57 Monoclonal Antibody (Clone:TB01)
|Amount :||0.1 mg|
|Isotype :||Mouse IgM|
|Purification :||Purified by protein-A affinity chromatography|
|Content :||Antibody suspended in Tris buffered saline (TBS) solution with 15 mM sodium azide|
|Storage condition :||Store at 2-8°C. Do not freeze.|
|Immunogen Information :||A pool of neuroblastoma cell lines|
CD57, also known as HNK1 or Leu7, is a sulphated trisaccharide (3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc) attached to several glycoproteins, including CD56, myelin glycoprotein PO, and neural cell adhesion molecule L1, as well as on glycolipids and chondroitin sulphate proteoglycans in the nervous system. It serves as a NK cell marker and it is expressed on well differentiated prostate cancers and uveal and cutaneous melanoma. CD57+ T cells are implicated as suppressors of T-cell responses.
Flow Cytometry Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Immunocytochemistry
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Subcellular location:||Cell membrane|
|Tissue Specificity:||Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.|
|BioGrid:||115514. 2 interactions.|