Anti-CD57 Monoclonal Antibody (Clone:TB01)

Product code: 30-1077

Clone name : TB01
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgM
Purification : Precipitation and chromatography
Content : Antibody suspended in Tris buffered saline (TBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Immunogen Information : A pool of neuroblastoma cell lines

CD57, also known as HNK1 or Leu7, is a sulphated trisaccharide (3-O-sulfoglucuronic acid beta1-3 Gal beta1-4 GlcNAc) attached to several glycoproteins, including CD56, myelin glycoprotein PO, and neural cell adhesion molecule L1, as well as on glycolipids and chondroitin sulphate proteoglycans in the nervous system. It serves as a NK cell marker and it is expressed on well differentiated prostate cancers and uveal and cutaneous melanoma. CD57+ T cells are implicated as suppressors of T-cell responses.

Flow Cytometry Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Immunocytochemistry

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Tissue Specificity: Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
BioGrid: 115514. 2 interactions.
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