Anti-CD81 Monoclonal Antibody (Clone:M38)

Product code: 30-1389

Clone name : M38
Clonality : Monoclonal
Reactivity : Human

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0.1 mg

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD81
Gene ID : 975
Uniprot ID : P60033
Alternative Name : CD81, TAPA1, TSPAN28
Immunogen Information : MOLT-4 (human T-ALL cell line)

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Flow cytometry: recommended dilution: 1 μg/ml.
Western blotting: recommended dilution: 1-2 μg/ml; positive control: Jurkat cells, non-reducing conditions.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Basolateral cell membrane
Post transnational modification: Not glycosylated.
Tissue Specificity: Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
BioGrid: 107413. 201 interactions.
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