Anti-GRPR antibody(3B12), Rabbit mAb
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| Amount : | 10 μg |
| Isotype : | Rabbit IgG |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % � 8% trehalose is added as protectants before lyophilization. |
| Storage condition : | Store at -20�C to -80�C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80�C (Avoid repeated freezing and thawing). |
| Gene : | GRPR |
| Uniprot ID : | P30550 |
| Alternative Name : | BB2;BB2R;BRS2 |
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
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For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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