Anti-Human CD133 Antibody (Clone : 293C3)

Product code: 30-2656

Clone name : 293C3
Clonality : Monoclonal
Application : FACS , WB, ICC
Reactivity : Human

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0.1 mg
$424.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG2b
Purification : Purified from cell culture supernatant by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : PROM1
Gene ID : 8842
Alternative Name : Prominin 1, PROM1, AC133, PROML1, STGD4,prominin 1
CD133 (prominin 1) is a 5-transmembrane glycoprotein with extracellular N- and intracellular C-terminus. CD133 function remains to be elucidated, but it can be used as a cancer stem cell marker. Its expression pattern in progenitor cells is similar to CD34, i.e. on hematopoietic stem cells in bone marrow, cord blood, neural stem cells, retinoblastoma, or endothelial precursor cells (not mature endothelial cells). It is being used for identification and isolation of hematopoietic stem cells, including isolation for stem cell transplantation. Expression of CD133 correlates with differentiation of human colon cancer cells.
Specificity : The mouse monoclonal antibody 293C3 recognizes the extracellular epitope 2 on human CD133 (CD133/2), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of human renal progenitors.
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