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    7. Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin

    Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin

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    Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin

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    Product code: 12-8023

    Clone name : KW-0761
    Clonality : Monoclonal
    Application : ELISA
    Reactivity : Human

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    Size
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    100 µg
    $599.00  $479.20 

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    • Product Info
    • Antigen Details
    • Description
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    Amount : 100 µg
    Isotype : Human IgG1k
    Content : Concentration : 0.5 mg/ml
    This Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
    Storage condition : This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
    Alternative Name : CD194; CKR-4; CCR-4; CCR4; K5-5
    Immunogen Information : Humanization of mouse anti-CCR4 mAb7.

    Expression Host : HEK-293

    This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Mogamulizumab. Clone KW-0761 recognizes human CD194 (CCR4). This product is for research use only.
    Clone KW-0761 (Mogamulizumab) is a research-grade, afucosylated, humanized monoclonal antibody generated from mouse anti-CCR4 mAb7 that targets human CCR4.1 CC chemokine receptor type 4 (CCR4) is a protein that belongs to the G protein-coupled receptor family and is a receptor for a variety of CC chemokines including MCP-1, MIP-1, RANTES, TARC, and Macrophage-derived chemokine. Chemokines are involved in the development, homeostasis, and function of the immune system and are known to regulate cell trafficking of various types of leukocytes. In a 2018 Phase I clinical trial, Mogamulizumab was found to decrease the number of HTLV-1–infected cells and the levels of inflammatory markers related to HTLV-1–Associated Myelopathy.3

    The suggested concentration for Mogamulizumab biosimilar antibody for staining cells in flow cytometry is <= 1.0 µg per 106 cells in a volume of 100 µl. Titration of the reagent is recommended for optimal performance for each application.ELISA

    For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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    Anti-Human CD194 (CCR4) (Mogamulizumab) – Fc Muted™ Biotin

    Product code: 12-8023
    *specify in mg or ml

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