Anti-Human CD226 Monoclonal Antibody (Clone:11A8)

Product code: 30-2925

Clone name : 11A8
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Non-Human Primates
Conjugate : Unconjugated

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0.1 mg

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified by protein-A affinity chromatography
Content : 1mg/ml, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene ID : 10666
Uniprot ID : Q15762
Alternative Name : DNAM1, PTA1, TLiSA1

CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.

Flow cytometry: Recommended dilution: 1-4 μg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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