Anti-Human Herpes Virus 8 (HHV8) Monoclonal Antibody(Clone: LN53)
Fig. 1: SDS-PAGE Analysis Purified HHV8 Rat Monoclonal Antibody (LN53). Confirmation of Purity and Integrity of Antibody.
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| Alternative Name : | HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV |
| Amount : | 100 µg |
| Isotype : | Rat IgG2c, kappa |
| Immunogen Information : | Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8 |
HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
ELISA (For coating use Ab at 1-5µg/ml, order Ab without BSA); Immunofluorescence (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (0.5-1µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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