Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Monoclonal Antibody(Clone: IL3RA/1531) (discontinued)

Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).

Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Monoclonal Antibody(Clone: IL3RA/1531) (discontinued)

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Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).

Fig. 2: Formalin-fixed, paraffin-embedded human Lymph Node stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).

Fig. 3: Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).

Fig. 4: SDS-PAGE Analysis Purified IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531). Confirmation of Integrity and Purity of Antibody.

Fig. 5: Analysis of Protein Array containing >19,000 full-length human proteins using CD123 Mouse Monoclonal Antibody (IL3RA/1531) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2589

Clone name :	IL3RA/1531
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	IL3RA
Gene ID :	3563
Uniprot ID :	P26951
Alternative Name :	CD123; hIL3Ra; IL-3R-alpha; IL-3RA; IL3RAX; IL3RAY; IL3RX; IL3RY; Interleukin-3 Receptor, alpha; Interleukin3 receptor; Interleukin3 receptor, Y-chromosomal
Immunogen Information :	Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary)

CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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