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  7. Anti-p53 Monoclonal Antibody (Clone:IHC053)-Ready to Use

Anti-p53 Monoclonal Antibody (Clone:IHC053)-Ready to Use

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Figure 1: Immunohistochemical analysis of p53 (Clone: IHC053) on Colon Cancer

Anti-p53 Monoclonal Antibody (Clone:IHC053)-Ready to Use

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Product code: 44-1061

Clone name : IHC053
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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7 ml
$363.00 

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Amount : 7 ml
Isotype : Mouse IgG2b
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : TP53
Gene ID : 7157
Uniprot ID : P04637
Alternative Name : TP53, P53
Immunogen Information : Recombinant Human p53

"p53, also known as tumor protein 53 or TP53, is a tumor suppressor and transcription factor that functions in a number of anti-cancer activities including DNA repair, cell-cycle arrest, and apoptosis in response to DNA damage or other stressors. Mutations in p53 are linked to a number of malignant tumors, including those of the breast, ovarian, bladder, colon, lung, and melanoma. Anti-p53 staining has been used to detect intratubular germ cell neoplasia, and also to distinguish between uterine serous carcinoma and endometrioid carcinoma."

This product is available in ready to use format, hence no dilution is required.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm
Post transnational modification: Sumoylated with SUMO1. Sumoylated at Lys-386 by UBC9.
Tissue Specificity: Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner. Isoform 2 is expressed in most normal tissues but is not detected in brain, lung, prostate, muscle, fetal brain, spinal cord and fetal liver. Isoform 3 is expressed in most normal tissues but is not detected in lung, spleen, testis, fetal brain, spinal cord and fetal liver. Isoform 7 is expressed in most normal tissues but is not detected in prostate, uterus, skeletal muscle and breast. Isoform 8 is detected only in colon, bone marrow, testis, fetal brain and intestine. Isoform 9 is expressed in most normal tissues but is not detected in brain, heart, lung, fetal liver, salivary gland, breast or intestine.
BioGrid: 113010. 1093 interactions.
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Anti-p53 Monoclonal Antibody (Clone:IHC053)-Ready to Use

Product code: 44-1061
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