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  7. Anti-p53 Tumor Suppressor Protein Polyclonal Antibody

Anti-p53 Tumor Suppressor Protein Polyclonal Antibody

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Fig. 1: Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with p53 Rabbit Polyclonal Antibody.

Anti-p53 Tumor Suppressor Protein Polyclonal Antibody
Anti-p53 Tumor Suppressor Protein Polyclonal Antibody

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Fig. 1: Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with p53 Rabbit Polyclonal Antibody.
Fig. 2: SDS-PAGE Analysis Purified p53 Rabbit Polyclonal Antibody. Confirmation of Purity and Integrity of Antibody.

Product code: 36-3303

Clone name : N/A
Clonality : Polyclonal
Application : FACS, IF, WB, IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Rabbit IgG
Content : 200 µg/ml of Ab Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : TP53
Gene ID : 7157
Uniprot ID : P04637
Alternative Name : Antigen NY-CO-13, BCC7, Cellular Tumor Antigen p53, LFS1, TP53, Transformation Related Protein 53 (TRP53), Tumor Protein p53, Tumor Suppressor p53
Immunogen Information : Recombinant full-length human TP53 protein
Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Flow Cytometry (0.5-1µg/million cells); Immunofluorescence (0.5-1µg/ml); Western Blot (0.5-1.0µg/ml); Immunohistochemistry (Formalin-fixed) (0.25-0.5µg/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-p53 Tumor Suppressor Protein Polyclonal Antibody

Product code: 36-3303
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