Anti-Perforin Monoclonal Antibody (Clone:dG9)
Figure 1: Flow cytometry intracellular staining pattern of human peripheral whole blood stained using anti-human Perforin (dG9) purified antibody
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2b |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Perforin is a 70 kDa cytolytic protein with structural and functional similarities to complement component 9 (C9). It is stored in cytoplasmic granules of cytotoxic T cells and NK cells and after its release it forms transmembrane pores in the target cells to kill it. As perforin is a key effector molecule for cell-mediated cytolysis, defects of its gene can cause severe disorders.
Flow Cytometry- intracellular staining, Immunoprecipitation, Immunohistochemistry (frozen sections), Immunocytochemistry
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cytoplasmic granule lumen, Secreted, Cell membrane, Endosome lumen |
| Post transnational modification: | N-glycosylated. |
| BioGrid: | 111542. 5 interactions. |
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