Anti-Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody(Clone: PODXL/2185)

Name: Anti-Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody(Clone: PODXL/2185)
Brand: Abeomics
SKU: 36-2949
Price: 520.0000 USD
Availability: InStock
Rating: 4 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with Podocalyxin Mouse Monoclonal Antibody (PODXL/2185).

Anti-Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Monoclonal Antibody(Clone: PODXL/2185)

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Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with Podocalyxin Mouse Monoclonal Antibody (PODXL/2185).

Fig. 2: Formalin-fixed, paraffin-embedded human Endometrium stained with Podocalyxin Mouse Monoclonal Antibody (PODXL/2185).

Fig. 3: SDS-PAGE Analysis Purified EGFR Mouse Monoclonal Antibody (GFR/2596). Confirmation of Integrity and Purity of Antibody.

Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using Podocalyxin Mouse Monoclonal Antibody (PODXL/2185). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2949

Clone name :	PODXL/2185
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	PODXL
Gene ID :	5420
Uniprot ID :	O00592
Alternative Name :	PODXL, PDXL, GCTM-2; Gp200; PCLP1; Pcx; Podocalyxin-like protein 1
Immunogen Information :	Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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