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  7. Anti-Rat CD8a Low Endotoxin Antibody (Clone : OX-8)

Anti-Rat CD8a Low Endotoxin Antibody (Clone : OX-8)

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Anti-Rat CD8a Low Endotoxin Antibody (Clone : OX-8)

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Product code: 30-2544

Clone name : OX-8
Clonality : Monoclonal
Application : WB
Reactivity : Rat

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0.1 mg
$364.00 

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  • Product Info
  • Antigen Details
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Format : Low Endotoxin
Amount : 0.1 mg
Isotype : Mouse IgG1 kappa
Purification : Purified by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Low endotoxin azide free phosphate buffered saline (PBS) solution, 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD8a
Gene ID : 24930
Alternative Name : Ly-2, Ly-B, Ly-35, Lyt-2,CD8a molecule
Immunogen Information : High Mw glycoproteins from rat thymocytes

The CD8a (CD8 alpha) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.
Specificity : The mouse monoclonal antibody OX-8 recognizes the hinge-like membrane-proximal extracellular domain of rat CD8a (32-34 kDa; alpha chain of the CD8 antigen).

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Anti-Rat CD8a Low Endotoxin Antibody (Clone : OX-8)

Product code: 30-2544
*specify in mg or ml

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