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  7. Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody(Clone: rSPTBN2/1778)

Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody(Clone: rSPTBN2/1778)

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Fig. 1: SDS-PAGE Analysis Purified SPTBN2 Recombinant Mouse Monoclonal Antibody (rSPTBN2/1778). Confirmation of Purity and Integrity of Antibody.

Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody(Clone: rSPTBN2/1778)

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Product code: 36-3199

Clone name : rSPTBN2/1778
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

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  • Product Info
  • Antigen Details
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Amount : 100 µg
Isotype : Mouse IgG1, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : SPTBN2
Gene ID : 6712
Uniprot ID : O15020
Alternative Name : Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2
Immunogen Information : Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

ELISA (Use Ab at 2-4µg/ml for coating) (Order Ab without BSA); Western Blot (1-2µg/ml);Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody(Clone: rSPTBN2/1778)

Product code: 36-3199
*specify in mg or ml

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