Anti-Sulfotransferase family 1E, estrogen-preferring, member 1 Monoclonal Antibody(Clone: CPTC-SULT1E1-1)
Fig. 1: Formalin-fixed, paraffin-embedded human Small Intestine stained with SULT1E1 Mouse Monoclonal Antibody (CPTC-SULT1E1-1).
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| Amount : | 100 µg |
| Isotype : | Mouse IgG2b, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | SULT1E1 |
| Gene ID : | 6783 |
| Uniprot ID : | P49888 |
| Alternative Name : | EST; EST-1;EST1; Estrogen sulfotransferase; estrogen-preferring; estrone sulfotransferase; ST1E1; STE; Sulfotransferase 1E1; Sulfotransferase ; Sulfotransferase estrogen preferring |
| Immunogen Information : | Recombinant full-length human SULT1E1 protein |
The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjµgation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thoµght to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, sµggesting a role for SULT1E1 in tumorigenesis.
Immunohistochemistry (Formalin-fixed) (0.5-1µg/ml for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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