Anti-TCL1 (T-Cell Marker) Monoclonal Antibody(Clone: TCL1/2078)

Name: Anti-TCL1 (T-Cell Marker) Monoclonal Antibody(Clone: TCL1/2078)
Brand: Abeomics
SKU: 36-3408
Price: 429.0000 USD
Availability: InStock
Rating: 4.9 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Spleen stained with TCL1 Mouse Monoclonal Antibody (TCL1/2078).

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Fig. 1: Formalin-fixed, paraffin-embedded human Spleen stained with TCL1 Mouse Monoclonal Antibody (TCL1/2078).

Fig. 2: Formalin-fixed, paraffin-embedded human Tonsil stained with TCL1 Mouse Monoclonal Antibody (TCL1/2078).

Fig. 3: SDS-PAGE Analysis Purified TCL1 Mouse Monoclonal Antibody (TCL1/2078). Confirmation of Purity and Integrity of Antibody.

Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using TCL1 Mouse Monoclonal Antibody (TCL1/2078). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3408

Clone name :	TCL1/2078
Application :	IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS


Gene :	TCL1A
Gene ID :	10232
Uniprot ID :	P56279
Alternative Name :	TCL1A; Lymphoma/leukemia, T-cell; Oncogene TCL1; P14 TCL1; T cell leukemia 1; T cell lymphoma 1; T cell lymphoma 1A; T-cell leukemia/lymphoma 1A; TCL1; TCL1A
Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Immunogen Information :	Recombinant human TCL1 protein fragment (around aa 2-109) (exact sequence is proprietary)

T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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