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  7. 36-3249

Anti-Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody(Clone: TGB/1968R)

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Anti-Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody(Clone: TGB/1968R)

Fig. 1: Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with Thyroglobulin Rabbit Recombinant Monoclonal Antibody (TGB/1968R).

Anti-Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody(Clone: TGB/1968R)
Anti-Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody(Clone: TGB/1968R)

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Fig. 1: Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with Thyroglobulin Rabbit Recombinant Monoclonal Antibody (TGB/1968R).
   
Fig. 1: Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with Thyroglobulin Rabbit Recombinant Monoclonal Antibody (TGB/1968R).
Fig. 2: SDS-PAGE Analysis of Purified <BR>Thyroglobulin Rabbit Recombinant Monoclonal Antibody (TGB/1968R). Confirmation of Purity and Integrity of Antibody.

Product code: 36-3249

Clone name : TGB/1968R
Application : IHC
Reactivity : Human

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  •   20 µg

  •  100 µg

  • $199.00 

  • $429.00 

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  • Antigen Details
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Gene : TG
Gene ID : 7038
Uniprot ID : P01266
Alternative Name : AITD3; hTG; TDH3; Tg; Tgn
Amount : 100 µg
Isotype : Rabbit IgG
Immunogen Information : Recombinant full-length human Thyroglobulin protein
Thyroglobulin is a 660kDa dimeric pre-protein with multiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even thoµgh sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Immunohistochemistry (Formalin-fixed) (0.5-1.0µg/ml for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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Anti-Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody(Clone: TGB/1968R)

Product code: 36-3249
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