Anti-Transthyretin (Prealbumin) Monoclonal Antibody(Clone: CPTC-TTR-1)
Fig. 1: SDS-PAGE Analysis Purified Transthyretin Mouse Monoclonal Antibody (CPTC-TTR-1). Confirmation of Purity and Integrity of Antibody.
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| Amount : | 100 µg |
| Isotype : | Mouse IgG2a, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | TTR |
| Gene ID : | 7276 |
| Uniprot ID : | P02766 |
| Alternative Name : | Transthyretin; PALB; HsT2651; prealbumin, amyloidosis type 1; ATTR; TBPA; CTS; CTS1; carpal tunnel syndrome 1; thyroxine-binding prealbumin; prealbumin; HEL111; TTR protein; Epididymis luminal protein 111; prealbumin thyroxine binding; senile systemic amyloidosis antibody |
| Immunogen Information : | Recombinant human full-length protein |
Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thoµght to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Althoµgh the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thoµght to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).
ELISA (For coating, order Ab without BSA); Western Blot (1-2µg/ml)Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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