Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3081)

Name: Anti-Uroplakin 1B (Urothelial Differentiation Marker) Monoclonal Antibody(Clone: UPK1B/3081)
Brand: Abeomics
SKU: 36-3346
Price: 429.0000 USD
Availability: InStock
Rating: 4.1 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081).

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Fig. 1: Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081).

Fig. 2: Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081).

Fig. 3: Formalin-fixed, paraffin-embedded human Urothelial Carcinoma stained with Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081).

Fig. 4: SDS-PAGE Analyis Purified Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081). Confirmation of Purity and Integrity of Antibody.

Fig. 5: Analysis of Protein Array containing more than 19,000 full-length human proteins using Uroplakin 1B Mouse Monoclonal Antibody (UPK1B/3081) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3346

Clone name :	UPK1B/3081
Application :	ELISA, IHC
Reactivity :	Human

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For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS


Gene :	UPK1B
Gene ID :	7348
Uniprot ID :	O75841
Alternative Name :	Tetraspanin-20; Tspan-20; TSPAN20; UP1b; UPIb; UPK1B; Uroplakin-1b
Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Immunogen Information :	Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane throµgh AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order Ab without BSA); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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