Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
      • Cell Lines
        • Primary Cells
        • Reporter Cell Lines
        • Stable Cell Lines
      • Kits and Reagents
        • Inhibitor Screening Kit
        • Molecular Biology Kits
        • ELISA Kits
        • Apoptosis Detection kits
        • Luciferase reporter assay kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Immune-Check Point
      • Tissue Microarray
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Cancer Marker
  6. /
  7. Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)

Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)

Share:

Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with Monospecific Mouse Monoclonal Antibody to VISTA (VISTA/3006).

Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)
Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)
Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)

Roll over image to zoom in

   
Fig. 1: Formalin-fixed, paraffin-embedded human Placenta stained with Monospecific Mouse Monoclonal Antibody to VISTA (VISTA/3006).
Fig. 2: SDS-PAGE Analysis Purified Monospecific Mouse Monoclonal Antibody to VISTA (VISTA/3006). Confirmation of Integrity and Purity of Antibody.
Fig. 3: Analysis of Protein Array containing more than 19,000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to VISTA (VISTA/3006). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Product code: 36-3148

Clone name : VISTA/3006
Clonality : Monoclonal
Application : ELISA, IHC
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   20 µg

  •  100 µg

  • $199.00 

  • $459.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • Review   (0)
Amount : 100 µg
Isotype : Mouse IgG2b, kappa
Content : 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : VSIR
Gene ID : 64115
Uniprot ID : Q9H7M9
Alternative Name : B7H5; DD1alpha; GI24; PD-1H; PDCD1 homolog; Platelet receptor Gi24; PP2135; Stress-induced secreted protein 1 (SISP1); V domain Ig suppressor of T cell activation; V Set Immuno-regulatory Receptor
Immunogen Information : Recombinant full-length human VISTA protein
VISTA / GI24 is a transmembrane protein expressed in bone, on embryonic stem cells (ESCs), and on tumor cell surfaces. On ESC s, Gi24 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state. On tumor cells, Gi24 both promotes MT1-MMP expression and activity and serves as a substrate for MT1-MMP. This increases the potential for cell motility. Mature human Gi24 contains a 162aa extracellular region with one V-type Ig-like domain and a 96aa cytoplasmic domain. Human Gi24 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30kDa extracellular fragment plus a 25-30kDa membrane-bound fragment. VISTA is a negative checkpoint regulator and is expressed on myeloid cells, T-cells and human TILs (tumor infiltrating lymphocytes) on MDSCs (myeloid-derived suppressor cells) in the TME (tumor microenvironment). It is very likely both a ligand and receptor and is a promising target for cancer immunotherapy.

ELISA (For coating, order antibody without BSA);Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: LAMP3/2788)

Anti-CD63 (Late Endosomes Mark...

details-Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: LAMP3/2788)
Anti-PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody(Clone: PMEPA1/2697)

Anti-PMEPA1 / TMEPAI (Tumor Su...

details-Anti-PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Monoclonal Antibody(Clone: PMEPA1/2697)
Anti-Beta-2 Microglobulin (Renal Failure & Tumor Marker) Monoclonal Antibody(Clone: C21.48A1)

Anti-Beta-2 Microglobulin (Ren...

details-Anti-Beta-2 Microglobulin (Renal Failure & Tumor Marker) Monoclonal Antibody(Clone: C21.48A1)
Recombinant Hepatitis C Virus NS5 Genotype-1a

Recombinant Hepatitis C Virus ...

details-Recombinant Hepatitis C Virus NS5 Genotype-1a
Sars-Cov-2 Spike Glycoprotein S1 (SF9 cell line)

Sars-Cov-2 Spike Glycoprotein ...

details-Sars-Cov-2 Spike Glycoprotein S1 (SF9 cell line)
Anti-Small Cell Lung Carcinoma Antigen (SCLC Marker) Monoclonal Antibody(Clone: MOC-52)

Anti-Small Cell Lung Carcinoma...

details-Anti-Small Cell Lung Carcinoma Antigen (SCLC Marker) Monoclonal Antibody(Clone: MOC-52)
Anti-Spectrin Alpha 1 (Erythrocyte Marker) Monoclonal Antibody(Clone: SPTA1/1832)

Anti-Spectrin Alpha 1 (Erythro...

details-Anti-Spectrin Alpha 1 (Erythrocyte Marker) Monoclonal Antibody(Clone: SPTA1/1832)
Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: LAMP3/2790)

Anti-CD63 (Late Endosomes Mark...

details-Anti-CD63 (Late Endosomes Marker) Monoclonal Antibody(Clone: LAMP3/2790)
Monoclonal antibody to CREB1 (Clone: ABM5B73)

Monoclonal antibody to CREB1 (...

details-Monoclonal antibody to CREB1 (Clone: ABM5B73)
Anti-PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody(Clone: PDL1/2746)-PE

Anti-PD-L1 / PDCD1LG1 / CD274 ...

details-Anti-PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Monoclonal Antibody(Clone: PDL1/2746)-PE
Anti-CD86 (Dendritic Cells Maturation Marker) Monoclonal Antibody(Clone: BU63)

Anti-CD86 (Dendritic Cells Mat...

details-Anti-CD86 (Dendritic Cells Maturation Marker) Monoclonal Antibody(Clone: BU63)
Anti-SIGLEC1 / CD169 / Sialoadhesin Monoclonal Antibody(Clone: HSn 7D2)

Anti-SIGLEC1 / CD169 / Siaload...

details-Anti-SIGLEC1 / CD169 / Sialoadhesin Monoclonal Antibody(Clone: HSn 7D2)
Monoclonal Antibody to human CD73

Monoclonal Antibody to human C...

details-Monoclonal Antibody to human CD73
Anti-CA19-9/Sialyl Lewisa (GI Tumor Marker) Monoclonal Antibody(Clone: SPM588)(Discontinued)

Anti-CA19-9/Sialyl Lewisa (GI ...

details-Anti-CA19-9/Sialyl Lewisa (GI Tumor Marker) Monoclonal Antibody(Clone: SPM588)(Discontinued)

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Peroxidase conjugated Goat anti Mouse IgG (H+L)

Peroxidase conjugated Goat anti Mou...

details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

Related Products

Polyclonal Antibody to Neurofilament NF-L

Polyclonal Antibody to Neurofilament NF-L

Anti-DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) Monoclonal Antibody(Clone: DG1/2564R)

Anti-DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) Monoclonal Antibody(Clone: DG1/2564R)

Anti-GATA-3 (Breast and Urothelial Marker) Monoclonal Antibody(Clone: GATA3/2445)

Anti-GATA-3 (Breast and Urothelial Marker) Monoclonal Antibody(Clone: GATA3/2445)

New Products

SARS-CoV-2 (2019-nCoV) Spike S1(N439K)- His Tag Protein

SARS-CoV-2 (2019-nCoV) Spike S1(N439K)- His Tag Protein

SARS-CoV-2 Spike S1 Mutant Sampler Set

SARS-CoV-2 Spike S1 Mutant Sampler Set

SARS-CoV-2 (2019-nCoV) Spike S1(D614G)- His Tag Protein

SARS-CoV-2 (2019-nCoV) Spike S1(D614G)- His Tag Protein

close

Please Login to write a Review !!


close

Anti-VISTA / GI24 (Negative Regulator of Immune Response) Monoclonal Antibody(Clone: VISTA/3006)

Product code: 36-3148
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • recmAb™
  • Cell Lines
  • Kits and Reagents
  • Immune-Check Point
  • Tissue Microarray
  • Ligands and Inhibitors
  • Recombinant Proteins

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2021 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart