Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Monoclonal Antibody(Clone: VWF/1767)

Name: Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Monoclonal Antibody(Clone: VWF/1767)
Brand: Abeomics
SKU: 36-3373
Price: 520.0000 USD
Availability: InStock
Rating: 4.7 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Spleen stained with vWF Mouse Monoclonal Antibody (VWF/1767).

Anti-von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Monoclonal Antibody(Clone: VWF/1767)

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Fig. 1: Formalin-fixed, paraffin-embedded human Spleen stained with vWF Mouse Monoclonal Antibody (VWF/1767).

Fig. 2: SDS-PAGE Analysis Purified vWF Monoclonal Antibody (VWF/1767). Confirmation of Purity and Integrity of Antibody.

Fig. 3: Analysis of Protein Array containing >19,000 full-length human proteins using vWF Mouse Monoclonal Antibody (VWF/1767) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Product code: 36-3373

Clone name :	VWF/1767
Clonality :	Monoclonal
Application :	ELISA, IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	VWF
Gene ID :	7450
Uniprot ID :	P04275
Alternative Name :	Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
Immunogen Information :	Recombinant fragment (around aa1815-1939) of human vWF protein (exact sequence is proprietary)

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers althoÂµgh not all tumors of endothelial differentiation contain this antigen.

ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA);Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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