G alpha 15 Stable Cell Line-GCGR-HEK293-Human
|Amount :||2 vials|
|Content :||Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO|
|Storage condition :||Immediately upon receipt, store in liquid nitrogen.|
|Alternative Name :||Human Recombinant Glucagon Receptor Stable Cell Line|
Glucagon regulates blood glucose via control of hepatic glycogenolysis and gluconeogenesis and via regulation of insulin release from the beta cell. Pharmacological administration of glucagon increases blood glucose in normal and diabetic subjects, and produces positive inotropic and chronotropic cardiovascular effects, relaxation of smooth muscle in the gastrointestinal tract and stimulation of growth hormone secretion. The actions of glucagon are mediated via a single adenylate cyclase-coupled glucagon receptor that also couples to the phospholipase C-inositol phosphate (PLC-IP) pathway leading to Ca2+ release from intracellular stores.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors.
Culture Medium: DMEM, 10% FBS, 50 µg/ml Hygromycin B, 300 µg/ml G418
For Research Use Only. Not for use in diagnostic/therapeutics procedures.