Gqi5 Stable Cell Line-SST1-CHO-K1-Human
|Amount :||2 vials|
|Content :||Each Vial contains cells in 45% culture medium, 45% FBS, 10% DMSO|
|Storage condition :||Immediately upon receipt, store in liquid nitrogen.|
|Alternative Name :||Human Recombinant SST1 Somatostatin Receptor Stable Cell Line|
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SST1 receptor is a Gi/Go-coupled GPCR which is expressed in pancreatic islets, pituitary, Cerebellum (Purkinje cells), frontal cortex (pyramidal cells), hippocampus (CA1-4 subfields and some granule cells of the dentate gyrus). It inhibits cAMP accumulation and stimulates tyrosine phosphatase activity, it also can antiproliferation.The SST1-expressing stable cell line was made in CHO-K1/Gqi5 host cell and optimized for calcium assays.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting and analyzing receptors.
Culture Medium: Ham's F12, 10% FBS
For Research Use Only. Not for use in diagnostic/therapeutics procedures.