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  7. Monoclonal Antibody to RIG-I (Clone: ABM40B5)

Monoclonal Antibody to RIG-I (Clone: ABM40B5)

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Fig-1: Western blot analysis of RIG-I. Anti- RIG-I antibody (Clone: ABM40B5) was used at 2 µg/ml on K562 lysates.

Monoclonal Antibody to RIG-I (Clone: ABM40B5)
Monoclonal Antibody to RIG-I (Clone: ABM40B5)
Monoclonal Antibody to RIG-I (Clone: ABM40B5)

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Fig-1: Western blot analysis of RIG-I. Anti- RIG-I antibody (Clone: ABM40B5) was used at 2 µg/ml on K562 lysates.
Fig-2 : Immunohistochemical analysis of RIG-I  in human prostate tissue using RIG-I  antibody (Clone: ABM40B5) at 5 µg/ml.
Figure-3: Intracellular flow cytometric analysis of RIG-I in K562 Cell line using 0.5 µg/10^6 cells of Anti-RIGI antibody (ABM40B5). Green represent isotype control and red represent Anti-RIG I antibody (10-4102 Abeomics). Goat anti-mouse PE conjugate was used as secondary.

Product code: 10-4102

Clone name : ABM40B5
Clonality : Monoclonal
Application : IHC, FACS, WB
Reactivity : Human

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Order now and get it on Friday January 22, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

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Same-day delivery in San Diego available for the following zip codes:

92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
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  •   25 µg

  •  100 µg

  • $90.00 

  • $270.00 

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Shipping Info:

Order now and get it on Friday January 22, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

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Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : DDX58
Gene ID : 23586
Uniprot ID : O95786
Alternative Name : DDX58
Immunogen Information : A partial length recombinant human RIG-I protein (amino acids 1-220) was used as the immunogen for this antibody.

RIG-I or Probable ATP-dependent RNA helicase DDX58 or simply DDX58 is a RNA helicase enzyme with two isoforms (106 and 101 kDa). RIG-I belongs to the DEAD/H box family and is involved in several cellular responses including RNA binding and alteration of RNA secondary structure. RIG-1 acts as sensor of viral nucleic acids thus activating a cascade of antiviral responses including the induction of type I interferons and pro-inflammatory cytokines. Generally it remains as a monomer but upon activation by viral dsRNA it homomultimerizes and interacts with mitochondria antiviral signaling protein (MAVS/IPS1) which activating a cascade of reactions to produce specific interferon. RIG-1 is mostly expressed in vascular smooth cells.

Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml, Flowcytometric analysis: 0.5-1µg/10^6 cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Cell projection, Cytoplasm, Cell junction
Post transnational modification: Sumoylated, probably by MUL1; inhibiting its polyubiquitination.
Tissue Specificity: Present in vascular smooth cells (at protein level).
BioGrid: 117121. 43 interactions.
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Monoclonal Antibody to RIG-I (Clone: ABM40B5)

Product code: 10-4102
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