Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
        • Primary Cells
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Apoptosis
  6. /
  7. Monoclonal antibody to DR4 (Clone: ABM1B11 )

Monoclonal antibody to DR4 (Clone: ABM1B11 )

Share:

Fig.1: Intracellular FLOW analysis of Jurkat cells using 0.5 ug of DR4 antibody (Clone: ABM1B11). Isotype contol mouse IgG1 (ABEOMICS) was used. Goat Anti-mouse PE was used as secondary antibody.

Monoclonal antibody to DR4 (Clone: ABM1B11 )
Monoclonal antibody to DR4 (Clone: ABM1B11 )

Roll over image to zoom in

   
Fig.1: Intracellular FLOW analysis of Jurkat cells using 0.5 ug of DR4 antibody (Clone: ABM1B11). Isotype contol mouse IgG1 (ABEOMICS) was used. Goat Anti-mouse PE was used as secondary antibody.
Fig.2: Expression analysis of DR-4. Anti-DR4 antibody (Clone: ABM1B11) was tested at 2 µg/ml on K562 lysate.

Product code: 10-1002

Clone name : ABM1B11
Clonality : Monoclonal
Application : FACS, WB
Reactivity : Human

Shipping Info:

Order now and get it on Tuesday March 09, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Local delivery areas

Same-day delivery in San Diego available for the following zip codes:

92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $90.00 

  • $270.00 

Add to Wish List

Bulk Order

Shipping Info:

Order now and get it on Tuesday March 09, 2021

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : TNFRSF10A
Gene ID : 8797
Uniprot ID : O00220
Alternative Name : TNFRSF10A, APO2, DR4, TRAILR1
Immunogen Information : A partial length recombinant human DR4 protein (amino acids 2-203 was used as an immunogen for this antibody.

Death receptor 4 (DR4) or TRAIL-R1, a member of the tumor necrosis factor receptor superfamily, is a cell surface receptor that triggers the apoptotic machinery upon binding to its ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. DR4 expression is enhanced by DNA damage whether induced by ionizing radiation or by chemotherapeutic agents. On binding DR4, TRAIL induces cell death via caspase-dependent apoptosis. DR4 mediates oligomeric Abeta induction of extrinsic apoptotic pathways in human microvascular cerebral endothelial cells with activation of both caspase-8 and caspase-9. It is considered a promising molecular target for cancer therapy.

Western blot analysis: 2-4 µg/ml, FACS analysis- 0.5-1 µg/10^6 Cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
Tissue Specificity: Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells.
BioGrid: 114325. 50 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Anti-Human Immunodeficiency Virus Type-1 p24 (HIV1-p24) Monoclonal Antibody(Clone: HIV1-24/661)

Anti-Human Immunodeficiency Vi...

details-Anti-Human Immunodeficiency Virus Type-1 p24 (HIV1-p24) Monoclonal Antibody(Clone: HIV1-24/661)
Anti-CD284 (Toll-Like Receptor 4) Monoclonal Antibody(Clone: TLR4/230)

Anti-CD284 (Toll-Like Receptor...

details-Anti-CD284 (Toll-Like Receptor 4) Monoclonal Antibody(Clone: TLR4/230)
Anti-14-3-3E / Tryptophan 5-Monooxygenase Monoclonal Antibody(Clone: CPTC-YWHAE-1)

Anti-14-3-3E / Tryptophan 5-Mo...

details-Anti-14-3-3E / Tryptophan 5-Monooxygenase Monoclonal Antibody(Clone: CPTC-YWHAE-1)
Recombinant Human IL-4(Discontinued)

Recombinant Human IL-4(Discont...

details-Recombinant Human IL-4(Discontinued)
Recombinant Hepatitis C Virus NS5 Genotype-2b

Recombinant Hepatitis C Virus ...

details-Recombinant Hepatitis C Virus NS5 Genotype-2b
Anti-CD71 / Transferrin Receptor (TFRC) Monoclonal Antibody(Clone: TFRC/1149)

Anti-CD71 / Transferrin Recept...

details-Anti-CD71 / Transferrin Receptor (TFRC) Monoclonal Antibody(Clone: TFRC/1149)
CD5 Recombinant Protein

CD5 Recombinant Protein

details-CD5 Recombinant Protein
Anti-SOX9 / SRY-box 9 Monoclonal Antibody(Clone: rSOX9/2288)(Discontinued)

Anti-SOX9 / SRY-box 9 Monoclon...

details-Anti-SOX9 / SRY-box 9 Monoclonal Antibody(Clone: rSOX9/2288)(Discontinued)
SARS-CoV-2 (Spike RBD) IgG Serological ELISA Kit with false positive control

SARS-CoV-2 (Spike RBD) IgG Ser...

details-SARS-CoV-2 (Spike RBD) IgG Serological ELISA Kit with false positive control
Anti-HSP70 Monoclonal Antibody (Clone : C92F3A-5)

Anti-HSP70 Monoclonal Antibody...

details-Anti-HSP70 Monoclonal Antibody (Clone : C92F3A-5)
Polyclonal Antibody to Anti-Glut1 Antibody(Discontinued)

Polyclonal Antibody to Anti-Gl...

details-Polyclonal Antibody to Anti-Glut1 Antibody(Discontinued)
Nrf2 Leeporter™ Luciferase Reporter-MCF7 Cell Line

Nrf2 Leeporter™ Luciferase R...

details-Nrf2 Leeporter™ Luciferase Reporter-MCF7 Cell Line
AT1 Stable Cell Line-293T-Human(Currently Unavailable)

AT1 Stable Cell Line-293T-Huma...

details-AT1 Stable Cell Line-293T-Human(Currently Unavailable)
Biotinylated Recombinant Rabbit Monoclonal Antibody  to Human IgG1 (Clone: RM117)(Discontinued)

Biotinylated Recombinant Rabbi...

details-Biotinylated Recombinant Rabbit Monoclonal Antibody  to Human IgG1 (Clone: RM117)(Discontinued)

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Peroxidase conjugated Goat anti Mouse IgG (H+L)

Peroxidase conjugated Goat anti Mou...

details-Peroxidase conjugated Goat anti Mouse IgG (H+L)

Related Products

Mouse Monoclonal Antibody to CASP3 (Clone: 1262CT521.280.101)(Discontinued)

Mouse Monoclonal Antibody to CASP3 (Clone: 1262CT521.280.101)(Discontinued)

Anti-CD266 / TWEAK R Monoclonal Antibody (Clone:ITEM-4)-Low Endotoxin

Anti-CD266 / TWEAK R Monoclonal Antibody (Clone:ITEM-4)-Low Endotoxin

Mouse Anti-Bax

Mouse Anti-Bax

New Products

Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand (C-6His)

Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand (C-6His)

Phospho-Btk (Tyr551) (Clone: G12) rabbit mAb SureLight488 conjugate

Phospho-Btk (Tyr551) (Clone: G12) rabbit mAb SureLight488 conjugate

Recombinant Mouse Tissue Factor (C-6His)

Recombinant Mouse Tissue Factor (C-6His)

close

Please Login to write a Review !!


close

Monoclonal antibody to DR4 (Clone: ABM1B11 )

Product code: 10-1002
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2021 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart