Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Other Kits
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
      • sdMAB ™
        • Shark sdMAB ™
        • Alpaca sdMAB ™
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Apoptosis
  6. /
  7. Monoclonal antibody to DR4 (Clone: ABM1B11 )

Monoclonal antibody to DR4 (Clone: ABM1B11 )

Share:

Fig.1: Intracellular FLOW analysis of Jurkat cells using 0.5 µgof DR4 antibody (Clone: ABM1B11). Isotype contol mouse IgG1 (ABEOMICS) was used. Goat Anti-mouse PE was used as secondary antibody.

Monoclonal antibody to DR4 (Clone: ABM1B11 )
Monoclonal antibody to DR4 (Clone: ABM1B11 )

Roll over image to zoom in

   
Fig.1: Intracellular FLOW analysis of Jurkat cells using 0.5 µgof DR4 antibody (Clone: ABM1B11). Isotype contol mouse IgG1 (ABEOMICS) was used. Goat Anti-mouse PE was used as secondary antibody.
Fig.2: Expression analysis of DR-4. Anti-DR4 antibody (Clone: ABM1B11) was tested at 2 µg/ml on K562 lysate.

Product code: 10-1002

Clone name : ABM1B11
Clonality : Monoclonal
Application : FACS, WB
Reactivity : Human

Shipping Info:

Order now and get it on Tuesday September 26, 2023

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Local delivery areas

Same-day delivery in San Diego available for the following zip codes:

92121, 92122, 92037, 92117, 92109, 92110, 92101, 92010, 92011, 92009, 92008
Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $110.00 

  • $290.00 

Add to Wish List

Bulk Order

Shipping Info:

Order now and get it on Tuesday September 26, 2023

Same day delivery FREE on San Diego area orders placed by 1.00 PM

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 100 µg
Isotype : Mouse IgG1 Kappa
Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : TNFRSF10A
Gene ID : 8797
Uniprot ID : O00220
Alternative Name : TNFRSF10A, APO2, DR4, TRAILR1
Immunogen Information : A partial length recombinant human DR4 protein (amino acids 2-203 was used as an immunogen for this antibody.

Death receptor 4 (DR4) or TRAIL-R1, a member of the tumor necrosis factor receptor superfamily, is a cell surface receptor that triggers the apoptotic machinery upon binding to its ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. DR4 expression is enhanced by DNA damage whether induced by ionizing radiation or by chemotherapeutic agents. On binding DR4, TRAIL induces cell death via caspase-dependent apoptosis. DR4 mediates oligomeric Abeta induction of extrinsic apoptotic pathways in human microvascular cerebral endothelial cells with activation of both caspase-8 and caspase-9. It is considered a promising molecular target for cancer therapy.

Western blot analysis: 2-4 µg/ml, FACS analysis- 0.5-1 µg/10^6 Cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
Tissue Specificity: Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells.
BioGrid: 114325. 50 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Monoclonal Antibody to human CD14

Monoclonal Antibody to human C...

details-Monoclonal Antibody to human CD14
Biotin Conjugated, Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)

Biotin Conjugated, Anti-CD31 /...

details-Biotin Conjugated, Anti-CD31 / PECAM-1 Monoclonal Antibody (Clone:MEM-05)
Polyclonal Antibody to SARS-CoV-2 nucleocapsid Protein Biotin Conjugated

Polyclonal Antibody to SARS-Co...

details-Polyclonal Antibody to SARS-CoV-2 nucleocapsid Protein Biotin Conjugated
CD200 Mouse

CD200 Mouse

details-CD200 Mouse
Anti-CD57 Monoclonal Antibody (Clone:TB01)

Anti-CD57 Monoclonal Antibody ...

details-Anti-CD57 Monoclonal Antibody (Clone:TB01)
Mouse IgG1 Isotype Control DyLight<sup>®</sup> 488 (Clone : MOPC-21)

Mouse IgG1 Isotype Control DyL...

details-Mouse IgG1 Isotype Control DyLight<sup>®</sup> 488 (Clone : MOPC-21)
Anti-CD147 / Basigin / Neurothelin Monoclonal Antibody (Clone:MEM-M6/6)-Low Endotoxin

Anti-CD147 / Basigin / Neuroth...

details-Anti-CD147 / Basigin / Neurothelin Monoclonal Antibody (Clone:MEM-M6/6)-Low Endotoxin
VISTA Stable Cell Line-H

VISTA Stable Cell Line-H

details-VISTA Stable Cell Line-H
Anti-CD142 Monoclonal Antibody (Clone:HTF-1)

Anti-CD142 Monoclonal Antibody...

details-Anti-CD142 Monoclonal Antibody (Clone:HTF-1)
Anti-CD70 Antibody (vorsetuzumab biosimilar) (SGN-70)

Anti-CD70 Antibody (vorsetuzum...

details-Anti-CD70 Antibody (vorsetuzumab biosimilar) (SGN-70)
Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use

Anti-PD-1 Monoclonal Antibody ...

details-Anti-PD-1 Monoclonal Antibody (Clone:IHC001)-Ready to Use
Anti-Human CTLA-4 (Ipilimumab) – Biotin

Anti-Human CTLA-4 (Ipilimumab)...

details-Anti-Human CTLA-4 (Ipilimumab) – Biotin
Monoclonal Antibody to DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker)(Clone : DOG-1.1)

Monoclonal Antibody to DOG-1 /...

details-Monoclonal Antibody to DOG-1 / TMEM16A / ANO1 (Gastrointestinal Stromal Tumor Marker)(Clone : DOG-1.1)
Anti-MSLN antibody(DM73), Rabbit mAb

Anti-MSLN antibody(DM73), Rabb...

details-Anti-MSLN antibody(DM73), Rabbit mAb

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Related Products

Polyclonal Antibody to Caspase 9

Polyclonal Antibody to Caspase 9

Anti-Perforin APC Mab (Clone:dG9)

Anti-Perforin APC Mab (Clone:dG9)

Anti-CD178 / Fas-L Monoclonal Antibody (Clone:NOK-1)

Anti-CD178 / Fas-L Monoclonal Antibody (Clone:NOK-1)

New Products

Anti-Hu CD68 FITC Mab(Y1/82A)

Anti-Hu CD68 FITC Mab(Y1/82A)

Anti-Hu IgE PE Mab(4H10)

Anti-Hu IgE PE Mab(4H10)

Anti-Hu CD172ab APC Mab(SE5A5)

Anti-Hu CD172ab APC Mab(SE5A5)

close

Please Login to write a Review !!


close

Monoclonal antibody to DR4 (Clone: ABM1B11 )

Product code: 10-1002
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™
  • sdMAB ™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart