Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Immunology
  6. /
  7. Monoclonal Antibody to human TNF-alpha

Monoclonal Antibody to human TNF-alpha

Share:

Figure-1: 10, 25 and 50 ng recombinant TNF-alpha was used as sample with antibody 10-3537 as primary antibody. A reduced sample treatment was used and a band of 17 kDa is shown

Monoclonal Antibody to human TNF-alpha

Roll over image to zoom in

   

Product code: 10-3537

Clone name : 52B83
Clonality : Monoclonal
Application : FACS, WB
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   100 µg

  •  500 µg

  • $754.00 

  • $1,745.00 

Add to Wish List

Bulk Order

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Amount : 500 µg
Isotype : Mouse IgG1
Content : 0.5 mg, 0.2 µm filtered protein G purified antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide.
Storage condition : Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Gene : TNF
Gene ID : 7124
Uniprot ID : P01375
Alternative Name : TNFA, TNFSF2, Cachectin, TNF-alpha

The monoclonal antibody 52B83 reacts with tumor necrosis factor alpha (TNF-alpha). TNF-alpha is a homotrimeric 17 kDa protein, that interacts with either one of the two types of TNF-receptors, termed I and II, leading to receptor cross-linking and signal transduction. The receptors differ strongly in their intra-cellular signaling pathways. TNF-alpha was originally described as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Furthermore,- TNF-alpha is found to be a central mediator in many inflammatory and immunological processes. It can be induced by various products of micro-organisms and by various cytokines leading to expression of a wide variety of- cytokines. The pro-inflammatory properties of- TNF-alpha play a central role in several auto-immune diseases such as rheumatoid arthritis and inhibition by neutralizing molecules have been shown to be beneficial in patients.

FACS analysis: This antibody was used to stain soluble TNF bound to TNF receptors. Cells were fixed in PBA containing 0.2% formaldehyde W: A reduced sample treatment and 15% SDS-Page was used. The band size observed is 17 kDa. IHC-F: 6-µm tissue sections were fixed in acetone for 10 minutes. Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
BioGrid: 112979. 269 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

Anti-TAG-72 Monoclonal Antibody (Clone:IHC072)-Ready to Use

Anti-TAG-72 Monoclonal Antibod...

details-Anti-TAG-72 Monoclonal Antibody (Clone:IHC072)-Ready to Use
Anti-Human CD340 APC (Clone : 24D2)

Anti-Human CD340 APC (Clone : ...

details-Anti-Human CD340 APC (Clone : 24D2)
Anti-p63 Monoclonal Antibody (Clone:IHC063)-Ready to Use

Anti-p63 Monoclonal Antibody (...

details-Anti-p63 Monoclonal Antibody (Clone:IHC063)-Ready to Use
Recombinant human PPT protein with C-terminal human Fc tag

Recombinant human PPT protein ...

details-Recombinant human PPT protein with C-terminal human Fc tag
Anti-beta-tubulin / TUBB Monoclonal Antibody (Clone:TU-13)

Anti-beta-tubulin / TUBB Monoc...

details-Anti-beta-tubulin / TUBB Monoclonal Antibody (Clone:TU-13)
Anti-Human IL-6 (Sarilumab)

Anti-Human IL-6 (Sarilumab)

details-Anti-Human IL-6 (Sarilumab)
Anti-Mouse CD49d Antibody (Clone : R1-2)

Anti-Mouse CD49d Antibody (Clo...

details-Anti-Mouse CD49d Antibody (Clone : R1-2)
Anti-TNAP PE (Clone : W8B2B10)

Anti-TNAP PE (Clone : W8B2B10)

details-Anti-TNAP PE (Clone : W8B2B10)
Anti-SARS-CoV-2 RBD antibody(DM55), Rabbit mAb

Anti-SARS-CoV-2 RBD antibody(D...

details-Anti-SARS-CoV-2 RBD antibody(DM55), Rabbit mAb
Leeporter™ Luciferase Assay Reagent- 1000 Test

Leeporter™ Luciferase Assay ...

details-Leeporter™ Luciferase Assay Reagent- 1000 Test
H3F3A Recombinant Protein

H3F3A Recombinant Protein

details-H3F3A Recombinant Protein
Anti-TFE3 Monoclonal Antibody (Clone:IHC672)

Anti-TFE3 Monoclonal Antibody ...

details-Anti-TFE3 Monoclonal Antibody (Clone:IHC672)
Celltase™ Cell Detachment Solution

Celltase™ Cell Detachment So...

details-Celltase™ Cell Detachment Solution
Anti-PSA Monoclonal Antibody (Clone:IHC654)-Ready to Use

Anti-PSA Monoclonal Antibody (...

details-Anti-PSA Monoclonal Antibody (Clone:IHC654)-Ready to Use

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

PE Conjugated, Anti-CD101 Monoclonal Antibody (Clone:BB27)

PE Conjugated, Anti-CD101 Monoclonal Antibody (Clone:BB27)

Anti-CD42b / GPIb alpha Monoclonal Antibody (Clone:HIP1)-PE Conjugated(Discontinued)

Anti-CD42b / GPIb alpha Monoclonal Antibody (Clone:HIP1)-PE Conjugated(Discontinued)

Anti-Lambda light chains Monoclonal Antibody (Clone:Rs4)

Anti-Lambda light chains Monoclonal Antibody (Clone:Rs4)

New Products

Recombinant Human ALK-2 (C-Fc)

Recombinant Human ALK-2 (C-Fc)

Recombinant Human MCM

Recombinant Human MCM

Recombinant Human Transcription initiation factor IIB/GTF2B(C-His)

Recombinant Human Transcription initiation factor IIB/GTF2B(C-His)

close

Please Login to write a Review !!


close

Monoclonal Antibody to human TNF-alpha

Product code: 10-3537
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart