Monoclonal Antibody to Mouse CD137(Clone: 3H3)-NALE
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| Format : | Low Endotoxin |
| Amount : | 100 µg |
| Isotype : | Rat IgG2a κ |
| Purification : | Protein A/G |
| Content : | This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Storage condition : | This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
4-1BB (CD137) is a costimulatory molecule expressed on the surface of activated T cells and plays a role in T-cell-mediated proliferative response. 4-1BB signal regulates CD28 co-stimulation in the targeted subset cells to favor Th1 development and maintain long-term cell growth. 4-1BB is also expressed on dendritic cells (DCs) and controls the duration, DC-T interaction, and, therefore, immunogenicity. Clone 3H3 antibody is an agonistic antibody that has been shown to stimulate 4-1BB signaling in vivo.
≤ 1.0 EU/mg as determined by the LAL method
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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