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  7. Monoclonal Antibody to Punctin-1 (clone: 1B2-8-2)

Monoclonal Antibody to Punctin-1 (clone: 1B2-8-2)

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Monoclonal Antibody to Punctin-1 (clone: 1B2-8-2)

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Product code: 10-3561

Clone name : 1B2-8-2
Clonality : Monoclonal
Application : ELISA, WB
Reactivity : Human

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  •   100 µg

  •  500 µg

  • $806.00 

  • $1,745.00 

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Amount : 500 µg
Isotype : Mouse IgG2b
Content : 0.2 µm filtered antibody solution in PBS containing 0.1% bovine serum albumin and 0.02% sodium azide.
Storage condition : Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year.
Gene : ADAMTSL1
Gene ID : 92949
Uniprot ID : Q8N6G6
Alternative Name : ADAMTSR1, C9orf94
Immunogen Information : thrombospondin repeat near the N-terminal

Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix. Monoclonal antibody 1B2-8-2 recognizes the first thrombospondin repeat near the N-terminal and reacts with molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained.

 

Subcellular location: Secreted
Post transnational modification: Disulfide bonds are present.
Tissue Specificity: Expressed primarily in adult skeletal muscle.
BioGrid: 124989. 7 interactions.
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Monoclonal Antibody to Punctin-1 (clone: 1B2-8-2)

Product code: 10-3561
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