Abeomics Logo
  • (0) Items
    • Items | total: $0.00 (0)
    • Your shopping cart is empty!

Abeomics Logo

Antibodies & Engineered Cell Lines™

  • Account
    • Login
    • Address Book
    • My Order
    • My Wish List
    • Open a New Ticket
  • (0) Items
    • Your shopping cart is empty!

  • About us
  • Products
      • Antibodies
        • Biosimilars
        • TLR and Innate Immunity
        • Apoptosis
        • Immunology
        • DNA methylation and Repair
        • Cell Signalling
        • Infectious Diseases
        • NF-kB Pathway
        • Cancer Marker
        • Loading Controls
        • Stem Cells
        • Development and Differentiation
        • Isotype Controls
        • Secondary Antibodies
        • Tag Antibodies
        • Miscellaneous
      • Cell Lines
        • Reporter Cell Lines
        • Stable Cell Lines
      • Ligands and Inhibitors
        • Peptide Inhibitors
        • Proteases inhibitors
        • TLR Ligands
        • Caspase Inhibitors
      • Recombinant Proteins
        • Recombinant Proteins
      • Immune-Check Point
      • Kits and Reagents
        • Luciferase reporter assay kits
        • Inhibitor Screening Kit
        • ELISA Kits
        • Molecular Biology Kits
        • Apoptosis Detection kits
        • Flowcytometry staining kits
        • Cell dissociation solutions
        • Western Blot membranes (Quick blots/ Q Blots)
      • Tissue Microarray
      • recmAb™
        • Recombinant Biosimilar Antibodies
        • Recombinant Rabbit Antibodies
        • Recombinant Mouse Antibodies
  • Pathways
      • All-Pathways

        View all pathways

      • interactive-pathways

        View all interactive pathways

  • Custom Service
    • Drug Discovery Screening Services
    • Stable Cell Line Development
    • Protein Production
    • Custom Antibody Development
  • Quick order
    • + Add More..

  • Support
  • Contact us
  • Distributors
  1. Catalog
  2. /
  3. Antibodies
  4. /
  5. Immunology
  6. /
  7. Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)

Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)

Share:

Figure-1 : Western blot analysis of IL-8 Antibody (Clone: 2A11D8) at 1 µg/ml on human recombinant IL-8 fusion protein . IRDye 800 Conjugated Goat Anti-Mouse IgG was used as secondary Antibody.

Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)
Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)
Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)

Roll over image to zoom in

   
Figure-1 : Western blot analysis of IL-8 Antibody (Clone: 2A11D8) at 1 µg/ml on human recombinant IL-8 fusion protein . IRDye 800 Conjugated Goat Anti-Mouse IgG was used as secondary Antibody.
Figure-2 : Sandwich ELISA analysis of matched antibody pairs using Human IL-8 Antibody (Clone: 2A11D8) 1) ELISA plate was coated with Human IL-8 Antibody (Clone: 2A11D8) 2) Human recombinant IL-8 protein at appropriate dilution was added into appropriate reaction wells 3) After a period of incubation, HRP conjugated Human IL-8 Antibody ((Clone.1A7C8 ,  4H7C7 and  4H8F8)) was added followed by proper period of incubation.
Figure-3 : Sandwich ELISA analysis of matched antibody pairs using Human IL-8 Antibody (2A11D8). 1) ELISA plate is coated with Human IL-8 Antibody (Clone: 2A11D8) 2) Human recombinant IL-8 protein at appropriate dilution is added into appropriate reaction wells 3) After a period of incubation, HRP conjugated Human IL-8 Antibody, mAb, Mouse (Clone. 3B1A8) is added followed by proper period of incubation.

Product code: 45-1053

Clone name : 2A11D8
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS
Write a review for this product on BioCompare
Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at support@abeomics.com

Download TDS MSDS

  • Product Info
  • Antigen Details
  • Description
  • Application Note
  • More
  • Review   (0)
Format : Purified
Amount : 40 µg
Isotype : Mouse IgG1, κ
Purification : Protein A chromatography
Content : 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage condition : The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Gene : CXCL8
Gene ID : 3576
Uniprot ID : P10145
Alternative Name : C-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, Emoctakin, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil chemotactic factor, MDNCF, Monocyte-derived neutrophil-activating peptide, MONAP, Neutrophil-activating protein 1, NAP-1, Protein 3-10C T-cell chemotactic factor
Immunogen Information : Amino acids sequence: MTSKLAVALL AAFLISAALC EGAVLPRSAK ELRCQCIKTY SKPFHPKFIK ELRVIESGPH CANTEIIVKL SDGRELCLDP KENWVQRVVE KELKRAENS

IL-8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins is proinflammatory and primarily mediates the activation and migration of neutrophils from peripheral blood into tissue. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL-8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology. Human IL-8 Antibody (2A11D8), mAb, Mouse was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide . The animals cells produce the protein, which stimulates the animals immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper, and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity, and native protein recognization.

ELISA Capture: 0.5-1 µg/ml
ELISA Detection: 0.05-0.2 µg/ml
Western blot: 1-2 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
Post transnational modification: Citrullination at Arg-27 prevents proteolysis, and dampens tissue inflammation, it also enhances leukocytosis, possibly through impaired chemokine clearance from the blood circulation.
BioGrid: 109790. 12 interactions.
There are currently no product reviews
Write a review on this product!

Customers who purchased this product also purchased

mProcalcitonin Recombinant Protein

mProcalcitonin Recombinant Pro...

details-mProcalcitonin Recombinant Protein
Anti-p16 Monoclonal Antibody (Clone:IHC116)

Anti-p16 Monoclonal Antibody (...

details-Anti-p16 Monoclonal Antibody (Clone:IHC116)
Anti-IDH1 R132H Monoclonal Antibody (Clone:IHC132)-Ready to Use

Anti-IDH1 R132H Monoclonal Ant...

details-Anti-IDH1 R132H Monoclonal Antibody (Clone:IHC132)-Ready to Use
Anti-TIGIT Antibody (tiragolumab biosimilar) (MTIG-7192-A)

Anti-TIGIT Antibody (tiragolum...

details-Anti-TIGIT Antibody (tiragolumab biosimilar) (MTIG-7192-A)
Recombinant human ITGB5 protein with C-terminal human Fc tag

Recombinant human ITGB5 protei...

details-Recombinant human ITGB5 protein with C-terminal human Fc tag
Anti-Human CD268 APC (Clone : 11C1)

Anti-Human CD268 APC (Clone : ...

details-Anti-Human CD268 APC (Clone : 11C1)
ProMatrilysin Recombinant Protein

ProMatrilysin Recombinant Prot...

details-ProMatrilysin Recombinant Protein
Anti-Human CD11a (Efalizumab)

Anti-Human CD11a (Efalizumab)

details-Anti-Human CD11a (Efalizumab)
Recombinant human IFNB protein with C-terminal human Fc tag

Recombinant human IFNB protein...

details-Recombinant human IFNB protein with C-terminal human Fc tag
Anti-Human CD344 Antibody (Clone : CH3A4A7)

Anti-Human CD344 Antibody (Clo...

details-Anti-Human CD344 Antibody (Clone : CH3A4A7)
TGF b 1 Recombinant Protein

TGF b 1 Recombinant Protein

details-TGF b 1 Recombinant Protein
Anti-Rat CD28 Low Endotoxin Antibody (Clone : JJ319)

Anti-Rat CD28 Low Endotoxin An...

details-Anti-Rat CD28 Low Endotoxin Antibody (Clone : JJ319)
Anti-Mouse CD49e PE (Clone : 5H10-27 (MFR5))

Anti-Mouse CD49e PE (Clone : 5...

details-Anti-Mouse CD49e PE (Clone : 5H10-27 (MFR5))
ProSpec 8-Band Marker

ProSpec 8-Band Marker

details-ProSpec 8-Band Marker

Most viewed Products

Recombinant Human Thioredoxin-Like 4A

Recombinant Human Thioredoxin-Like ...

details-Recombinant Human Thioredoxin-Like 4A
NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line

NF-kB Leeporter™ Luciferase Repor...

details-NF-kB Leeporter™ Luciferase Reporter-RAW264.7 Cell Line
Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)

Monoclonal Antibody to Human IL-1be...

details-Monoclonal Antibody to Human IL-1beta (Clone: ABM26G5)
Polyclonal Antibody to Beta actin

Polyclonal Antibody to Beta actin

details-Polyclonal Antibody to Beta actin
Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)

Monoclonal Antibody to Caspase-3 (P...

details-Monoclonal Antibody to Caspase-3 (Pro and Active) (Clone: ABM1C12)
Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)

Monoclonal antibody to Human PD-L1 ...

details-Monoclonal antibody to Human PD-L1 (Clone: ABM5F25)
Monoclonal Antibody to GAPDH (Clone: ABM22C5)

Monoclonal Antibody to GAPDH (Clone...

details-Monoclonal Antibody to GAPDH (Clone: ABM22C5)
Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Human Indoleamine 2,3-D...

details-Recombinant Human Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)
Monoclonal antibody to B7-H4 (Clone: ABM53A6)

Monoclonal antibody to B7-H4 (Clone...

details-Monoclonal antibody to B7-H4 (Clone: ABM53A6)
Polyclonal Antibody to Beta Tubulin

Polyclonal Antibody to Beta Tubulin

details-Polyclonal Antibody to Beta Tubulin

Related Products

Polyclonal Antibody to ROR alpha - 25 µg

Polyclonal Antibody to ROR alpha - 25 µg

Peroxidase Conjugated Anti-IgG (Fc) Monoclonal Antibody (Clone:EM-07)

Peroxidase Conjugated Anti-IgG (Fc) Monoclonal Antibody (Clone:EM-07)

Low Endotoxin Anti-NK1.1 / CD161bc Monoclonal Antibody (Clone:PK136)(Discontinued)

Low Endotoxin Anti-NK1.1 / CD161bc Monoclonal Antibody (Clone:PK136)(Discontinued)

New Products

Recombinant Human ERBB2 (C-His)

Recombinant Human ERBB2 (C-His)

Recombinant Human Myocyte-specific enhancer factor 2A/MEF2A(C-His)

Recombinant Human Myocyte-specific enhancer factor 2A/MEF2A(C-His)

Anti-PCSK9 antibody(DMC222), IgG1 Chimeric mAb

Anti-PCSK9 antibody(DMC222), IgG1 Chimeric mAb

close

Please Login to write a Review !!


close

Mouse Monoclonal Antibody to IL-8 (Clone : 2A11D8)(Discontinued)

Product code: 45-1053
*specify in mg or ml

Abeomics Logo

Antibodies & Engineered Cell Lines™

Tel : 858-263-4982

Fax : 858-247-7052

Email : support@abeomics.com

Connect with Us

  • Facebook
  • Twitter
  • Linkedin
  • YouTube

Products

  • Antibodies
  • Cell Lines
  • Ligands and Inhibitors
  • Recombinant Proteins
  • Immune-Check Point
  • Kits and Reagents
  • Tissue Microarray
  • recmAb™

Services

  • Drug Discovery Screening Services
  • Stable Cell Line Development
  • Protein Production
  • Custom Antibody Development

Quick order

+ Add More..

Newsletter

Posters and Flyers

© 2023 Abeomics. All rights reserved.
  • Blog
  • Sitemap
  • Terms
  • Privacy Policy
  • Legal
  • Email unsubscribe

Item added to cart successfully

No cart item available
Continue shopping View Cart