PD-L1 Stable Cell Line-CHO-K1-Mouse
Figure 1: FACS analysis of mouse PD-L1 expression in CHO-K1/mouse PD-L1 cells.
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| Amount : | 2 vials |
| Content : | Each Vial contains cells in 95% complete growth medium+ 5% DMSO |
| Storage condition : | Immediately upon receipt, store in liquid nitrogen. |
| Alternative Name : | CD274 ; B7-H; B7H1; PDCD1L1; PDCD1LG1; PDL1 |
Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by the CD274 gene. The formation of PD-1 receptor / PD-L1 or B7.1 receptor /PD-L1 ligand complex transmits an inhibitory signal which reduces the proliferation of these CD8+ T cells at the lymph nodes. After that PD-1 is also able to control the accumulation of foreign antigen specific T cells in the lymph nodes through apoptosis, which is further mediated by a downregulation of the Bcl-2 gene.
Application: Screen for antibodies through Flow Cytometry, Immunocytochemistry or Western blotting. Culture Medium: F12K, 10% FBS, 8 µg/ml Puromycin
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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