Polyclonal Antibody to S1P3 receptor, Edg-3

Product code: 11-10017

Clonality : Polyclonal
Application : WB
Reactivity : Human

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Available Pack Size(s)

  •   25 µg

  •  100 µg

  • $100.00 

  • $270.00 

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Shipping Info:

Order now and get it on Thursday December 12, 2024

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Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Gene : S1PR3
Gene ID : 1903
Uniprot ID : Q99500
Alternative Name : S1PR3, EDG3
Immunogen Information : A partial length recombinant S1P3 receptor, Edg-3 protein (amino acids 80-350) was used as the immunogen for this antibody.

S1PR3 (sphingosine-1phosphate receptor3) is a vascular barrier regulatory member of the S1P family of receptors (S1PR15) and a critical signaling molecule mediating cell proliferation, adhesion, angiogenesis, and vascular permeability. In a nitrated form protein in plasma it is found as a biomarker in patients with ALI (acute lung injury). S1PR3 plays an important role in promoting pulmonary inflammation, disrupting cell-cell junctions, and increasing lung permeability and alveolar flooding during inflammation.

Western blot analysis: 2-4 µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane
Tissue Specificity: Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.
BioGrid: 108227. 3 interactions.
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