Recombinant Human ACE2 Protein (C-hFc)
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| Alternative Name : | Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-ConvertingEnzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2 |
| Amount : | 100 µg |
Source : HEK293;
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensin I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor do not inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensin I and II as a carboxypeptidase and converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor do not inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
| Content : | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4 |
| Amino acid sequence : | Recombinant Human ACE2 Protein is produced by HEK293. The target gene encoding 18-740 is expressed with a hFc tag at the C-terminus. |
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