Recombinant Human Bone Marrow Proteoglycan/BMPG (C-His)
|Amount :||50 µg|
|Content :||Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4|
|AA sequence :||Recombinant Human Bone Marrow Proteoglycan is produced by Human cells system and the target gene encoding Leu17-Tyr222 is expressed with a 6His tag at the C-terminus.|
|Alternative Name :||Bone Marrow Proteoglycan; BMPG; Proteoglycan 2; Eosinophil Granule Major Basic Protein; EMBP; MBP; Pregnancy-Associated Major Basic Protein; PRG2; MBP|
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity reactions.