Recombinant human ICOS protein with C-terminal human Fc tag
|Amount :||50 µg|
|Purification :||The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.|
|Content :||Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.|
|Storage condition :||Store at -80°C for 12 months (Avoid repeated freezing and thawing)|
|Alternative Name :||ICOS, CD278, AILIM, Inducible T-cell costimulator|
The protein has a predicted molecular mass of 39.7 kDa after removal of the signal peptide. The apparent molecular mass of ICOS-hFc is approximately 55 kDa due to glycosylation.
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.