Recombinant Mouse Interferon gamma/IFN-gamma
|Amount :||50 µg|
|Content :||Lyophilized from a 0.2 um filtered solution of PBS, pH7.4|
|AA sequence :||Recombinant Mouse Interferon gamma is produced by our Mammalian expression system and the target gene encoding His23-Cys155 is expressed.|
|Alternative Name :||Ifng;Interferon gamma;IFN-gamma;interferon-gamma|
Mouse Interferon-gamma (IFN-gamma/IFNG) is a secreted protein that belongs to the type II (gamma) interferon family. IFNG is primarily expressed by T lymphocytes, and activated by specific antigens or mitogens. In addition to having antiviral activity, IFNG also has important immunoregulatory functions. It is a potent activator of macrophages and has antiproliferative effects on transformed cells as well as enhance the antitumor effects of the type I interferons. IFNG also functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis.