Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1731R)
|Gene ID :||1113|
|Uniprot ID :||P10645|
|Alternative Name :||Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II|
|Amount :||100 µg|
|Isotype :||Rabbit IgG, kappa|
|Immunogen Information :||Recombinant human full-length Chromogranin A protein|
|Purification :||Purified Ab with BSA and Azide at 200ug/ml|
|Content :||200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.|
|Storage condition :||Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.|
Does not react with rat.
MW : 68-75kDa; Positive Control : PC12 cells. Adrenal gland, bowel, parathyroid, pancreas, or pheochromocytoma.;Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistology (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|Subcellular location:||Secreted, Cytoplasmic vesicle|
|Post transnational modification:||Proteolytic processing gives rise to an additional longer form of catestatin (residues 358-390) which displays a less potent catecholamine release-inhibitory activity (PubMed:10781584). Plasmin-mediated proteolytic processing can give rise to additional shorter and longer forms of catestatin peptides (PubMed:17991725).|
|Tissue Specificity:||GE-25 is found in the brain.|
|BioGrid:||107538. 12 interactions.|