SARS-CoV-2 Inhibitor Screening Kit
Figure-1: Binding of human ACE2 to the Spike protein of SARS-CoV-2 is inhibited by anti-ACE2 (human), mAb (blocking) (AC384) Azide free (Cat No# 29-1005).
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| Amount : | 6 × 16 Tests |
| Content : | 6x16 well Format (96 tests) |
| Storage condition : | Please refer to the Manual |
| Alternative Name : | COVID-19 Inhibitor Screening Kit; 2019-nCoV Inhibitor Screening Kit; 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor Screening Kit |
Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome β-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19).SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor. Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Hameed, Noor S.; Arif, Inam Sameh; Al-Sudani, Basma Talib
Preventive treatment of coronavirus disease-2019 virus using coronavirus disease-2019-receptor-binding domain 1C aptamer by suppress the expression of angiotensin-converting enzyme 2 receptor.
Journal of Advanced Pharmaceutical Technology & Research 14(3):p 185-190, Jul–Sep 2023
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