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  7. Anti-Arginase-1 Monoclonal Antibody (Clone:IHC400)

Anti-Arginase-1 Monoclonal Antibody (Clone:IHC400)

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Figure 1: Immunohistochemical analysis of Arginase-1 (Clone: IHC400) on Colon

Anti-Arginase-1 Monoclonal Antibody (Clone:IHC400)

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Product code: 44-1003

Clone name : IHC400
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •  0.5 ml

  • $313.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG2b
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : ARG1
Gene ID : 383
Uniprot ID : P05089
Alternative Name : ARG1
Immunogen Information : Recombinant Human Arginase-1

"Arginase-1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginine and ammonia in the blood. Anti-Arginase-1 is highly specific for hepatocytes, and is therefore a sensitive and specific marker of benign and malignant hepatic tumors."

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Cytoplasmic granule
Tissue Specificity: Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).
BioGrid: 106878. 34 interactions.
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Anti-Arginase-1 Monoclonal Antibody (Clone:IHC400)

Product code: 44-1003
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